A series of novel arylpiperazines were synthesized and the target compounds evaluated for atypical antipsychotic activity in apomorphine induced climbing behavior (D2 antagonism). 5-HTP induced head twitches (5-HT2A antagonism) and catalepsy studies in albino mice. The physicochemical similarity of the target compounds with respect to standard drugs clozapine. ketanserine and risperid... https://www.havifrost.com/product-category/other/
Synthesis, Computational Studies and Preliminary Pharmacological Evaluation of New Arylpiperazines
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